Multi-organ age acceleration

Biomarker

1 paper1 finding

Humans1

Associations

Menopausal transition

upin humans1

1 study

Menopausal transition is associated with multi-organ age acceleration in humans.
“In women, the menopausal transition dominated the aging landscape and was associated with multi-organ age acceleration.”
Humans10-yearfemalesn = 1,250
Longitudinal dynamics of organ-specific proteomic aging clocks over a decade of midlife
bioRxiv : the preprint server for biology18 Feb 2026Preprint

Latest

2 in 12 months

European Journal of Heart Failure26 Sep

Proteomic multi-organ aging accelerates before adverse events in heart failure patients

Organ age gaps for the kidney, lung, and immune system predicted patient outcomes independently of standard clinical biomarkers.Organ age gaps for the kidney, lung, and immune system predicted patient outcomes independently of standard clinical biomarkers.

Cohort study of 557 peopleHeart failure

Paper

bioRxiv27 Feb

Longitudinal dynamics of organ-specific proteomic aging clocks over a decade of midlife

Preprint: cohort study of 1,250 peopleBiomarkers