Microsphere extravasation

1. Alzheimer's disease increases microsphere extravasation in mice (38% versus 30% of microspheres extravasated by day 14).

   “38% of microspheres were extravasated by day 14 in 3xTg mice, compared to only 30% in non-transgenic controls.”

   Animals3xTg Alzheimer's mice versus non-transgenic controls after microsphere-induced micro-occlusionsbrain14 days

   Differential effects of aging and Alzheimer’s disease on microemboli clearance in a mouse model of microinfarction

   bioRxiv (Cold Spring Harbor Laboratory)·4 Oct 2025Preprint

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