Microsatellite instability

1 paper1 finding

Humans1

Effects

1

Inflammation

upin humans1

1 study

Microsatellite instability increases inflammation in humans (+0.065 (unadjusted), +0.087 (adjusted)).
“MSI-high tumors showed greater tumor-normal inflammation amplification than non-MSI-high tumors (+0.065, P = 0.015), strengthening after adjustment (+0.087, P < 0.001).”
Humanspaired tumor and normal tissue
Age-related tumor mutational burden and inflammaging: a pan-cancer multi-omics study of treatment-naïve patients
Immuno-oncology technology30 Sep 2026

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