Microglial density

Biomarker2 papers4 findings

Animals2

Interventions

3

Tacedinaline

downin mice1Very low certainty

1 study

Tacedinaline decreases microglial density in mice.
AnimalsAPP/PS1 mice30 days
Histone Deacetylase Inhibitors Improve Memory Function and Decrease Neuropathology in APP/PS1 Mice · Research square · 26 Aug 2026 · Preprint

Tacedinaline →

Entinostat

downin mice1Very low certainty

1 study

Entinostat decreases microglial density in mice.
AnimalsAPP/PS1 mice30 days
Histone Deacetylase Inhibitors Improve Memory Function and Decrease Neuropathology in APP/PS1 Mice · Research square · 26 Aug 2026 · Preprint

Food deprivation

downin rats1Very low certainty

1 study

Food deprivation decreases microglial density in rats.
Animalsbrainup to 3 days
Food deprivation reduces microglia in the rat brain in association with reduced body temperature · Neuroscience · 26 Aug 2026

Food deprivation →

Associations

1

Body temperature

upin rats1

1 study

Body temperature is associated with microglial density in rats.
Animalsbrain
Food deprivation reduces microglia in the rat brain in association with reduced body temperature · Neuroscience · 26 Aug 2026

Latest

2

Research SquareAnimalsPreprint3 Sep

Histone Deacetylase Inhibitors Improve Memory Function and Decrease Neuropathology in APP/PS1 Mice

NeuroscienceAnimals26 Aug

Food deprivation reduces microglia in the rat brain in association with reduced body temperature