Frontiers in Microbiology
Nicotinamide mononucleotide reduced lens stiffness in mice
Lens stiffness measured 11.9 kilopascals at the higher dose, versus 17.9 in mice with diet-induced metabolic syndrome given no active compound.Lens stiffness measured 11.9 kilopascals at the higher dose, versus 17.9 in mice with diet-induced metabolic syndrome given no active compound.
Mouse study · 94 miceNicotinamide mononucleotide
Who was studied94 male and female C57BL/6J mice, against untreated metabolic-syndrome mice
What changedLens stiffness was lower with high-dose NMN than without NMN in metabolic-syndrome mice (difference −6.0 kPa)
The catchThe compression model ignores hydration-dependent deformation and regional differences in lens stiffness