Mechanical age

Biomarker

1 paper1 finding

  • Humans1

Associations

1

BRCA1/2 mutations or family history of breast cancer

upin human cells1

1 study
  1. BRCA1/2 mutations or family history of breast cancer is associated with mechanical age in human cells.

    “Cells from younger women carrying BRCA1/2 mutations or with a family history of breast cancer exhibited accelerated mechanical aging compared to age-matched controls.”

    CellsCompared with age-matched controlsprimary human mammary epithelial cellsfemales

    MechanoAge, a machine learning platform to identify individuals susceptible to breast cancer based on mechanical properties of single cells

    bioRxiv : the preprint server for biology12 Aug 2025Preprint

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