Mechano-RISQ

breast cancer risk backgrounds are associated with Mechano-RISQ in human cells.

“exhibited elevated Mechano-RISQ scores, which reflects accelerated biological ageing compared to age-matched controls (n = 18).”

CellsBRCA1/2 mutation carriers, women with family history of breast cancer, or tissue contralateral to a tumour-bearing breast; compared with age-matched controlsmammary epithelial cellfemales

MechanoAge, a machine learning platform to identify individuals susceptible to breast cancer based on mechanical properties of single cells

EBioMedicine·23 Apr 2026