ESC Congress 2026 Abstract
Exercise may protect hearts partly via a brown fat molecule in mice
In mice with diabetic heart disease, removing brown fat blunted the protective effects of voluntary exercise by causing a shortage of the signaling molecule maresin 2.In mice with diabetic heart disease, removing brown fat blunted the protective effects of voluntary exercise by causing a shortage of the signaling molecule maresin 2.
Mouse studyExercise
Who was studiedMice with diabetic cardiomyopathy
What changedRemoving brown fat blunted the cardioprotective effect of voluntary exercise against pathological cardiac remodeling and heart failure
The catchNLRP3 inflammasome and cytokine levels served as stand-ins; heart function was not measured