Lrpprc P27 dihydroxylation

Muscle wasting decreases Lrpprc P27 dihydroxylation in mice (~20%, p < 0.05).

“P27 dihydroxylation of Lrpprc declines (~20%; p < 0.05) with muscle wasting irrespective of the atrophic trigger.”

Animalsmuscle wasting induced by cancer, dexamethasone, or agingskeletal musclemales

Largely Distinct Post-Translational Modifications Differentiate Skeletal Muscle Wasting Caused by Cancer, Dexamethasone and Aging

Journal of cachexia, sarcopenia and muscle·1 Feb 2026