LPA DNA methylation

Biomarker

1 paper2 findings

  • Humans1

Interventions

1

Neighborhood socioeconomic deprivation

downin humans1

1 study
  1. Neighborhood socioeconomic deprivation decreases LPA DNA methylation in humans (b= -0.38, p=0.003).

    “two methylation sites associated negatively with NSD (cg17028067 b= -0.27, p=0.04; cg22888279 b= -0.38, p=0.003).”

    Humansfemalesn = 60

    Neighborhood Socioeconomic Deprivation Relates to Epigenetic Modification of the LPA gene and Potential Increase in Circulating Plasma Lp(a) Levels in African Americans: A Pilot Study

    AHA Scientific Sessions 2025 abstract3 Nov 2025

More on Neighborhood socioeconomic deprivation

Associations

1

Amygdala activity

downin humans1

1 study
  1. Amygdala activity is associated with LPA DNA methylation in humans (b= -0.28, p=0.03).

    “Amygdala activity was negatively associated with LPA -cg22888279 (b= -0.28, p = 0.03)”

    Humansfemalesn = 60

    Neighborhood Socioeconomic Deprivation Relates to Epigenetic Modification of the LPA gene and Potential Increase in Circulating Plasma Lp(a) Levels in African Americans: A Pilot Study

    AHA Scientific Sessions 2025 abstract3 Nov 2025

More on Amygdala activity

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