Loss of chromosome Y frequency

monocyte differentiation is associated with loss of chromosome Y frequency in humans (22.6% to 15.8%).

“with a progressive decrease along the transition trajectory from 22.6% to 15.8% (padj = 2.00 × 10−11)”

Humansalong the monocyte transition trajectorymonocytesmalesn = 416

Loss of Chromosome Y Associates With Altered Immune Cell Trajectories and X-Inactivation Features

Aging cell·1 May 2026