Lipid-based risk stratification model

1. Lipid-based risk stratification model predicts septic shock in humans (AUC: 0.87 training, 0.82 validation).

   “A risk stratification model incorporating six key lipids (LPC(19:0), PC(P-19:0), SM 32:3;2O(FA 16:3), PC(P-20:0), PC(O-18:1/20:3), CE(15:0)) and age accurately predicted septic shock”

   Humanstraining AUC: 0.87, validation AUC: 0.82

   Plasma lipidomic signatures reveal age-associated patterns of septic shock risk and immune dysregulation in sepsis

   Frontiers in immunology·19 Nov 2025

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