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LINE1 methylation

Biomarker

1 paper2 findings

  • Animals1

Associations

2

Body size

downin dogs1

1 study

  1. Body size is associated with LINE1 methylation in dogs (largest dogs lost 0.26% more LINE1 methylation per year than smallest dogs).

    “the largest dogs lost 0.26% more LINE1 methylation per year than the smallest dogs.”

    Animalslargest dogs compared with smallest dogsimmune cells

    DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project

    bioRxiv : the preprint server for biology17 Oct 2024Preprint

Chronological age

downin dogs1

1 study

  1. Chronological age is associated with LINE1 methylation in dogs (40% of all LINE1 regions hypomethylated with age).

    “were the most frequently hypomethylated with age (FDR < 0.05, 40% of all LINE1 regions).”

    Animalsimmune cellsn = 864

    DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project

    bioRxiv : the preprint server for biology17 Oct 2024Preprint

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