Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Dementia

upin humans1OR 2.8

1 study
  1. Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change raises the risk of dementia in humans (OR = 2.80; 95% CI = 1.53, 5.12).

    “Limbic-predominant Age-related TDP-43 Encephalopathy neuropathologic change (OR = 2.80; 95% CI = 1.53, 5.12)”

    Humansin participants with intermediate/high ADNCbrain70% womensn = 235

    Contribution of health history and neuropathologic changes to the likelihood of dementia in those with intermediate/high Alzheimer's pathology: findings from The 90 + Study

    Acta neuropathologica6 Apr 2026

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