Left ventricular end diastolic wall stress

1. Left ventricular end diastolic wall stress is associated with incident heart failure in humans (aHR 1.019 per 1-unit increase; 95% CI 1.014–1.024).

   “each 1-unit increase in LVEDWS significantly associated with an increased risk of incident HF (aHR: 1.019; 95%CI 1.014-1.024)”

   HumansClinically referred for echocardiography, without prevalent heart failure or ≥ moderate valve disease; multivariable-adjusted associationleft ventricleMedian 3.7 years; maximum 8.2 years54% femalessn = 29,246

   Non-invasive Left Ventricular End Diastolic Wall Stress and the Risk of Incident Heart Failure in a Clinical Population

   The American journal of cardiology·14 Oct 2026

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