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Late inward sodium current

Biomarker

1 paper studies it1 finding

  • Animals1

Interventions

1

Gonadectomy

upin mouse cells1

1 study

  1. Gonadectomy increases late inward sodium current in mouse cells (-2.4 ± 0.4 vs. -1.2 ± 0.2 pA/pF, P = 0.002).

    “INa,L was also larger in GDX than sham (-2.4 ± 0.4 vs. -1.2 ± 0.2 pA/pF; P = 0.002).”

    Cellsgonadectomy vs. shamventricular myocytesmales

    Chronic testosterone deficiency increases late inward sodium current and promotes triggered activity in ventricular myocytes from aging male mice

    American journal of physiology. Heart and circulatory physiologyJun 30, 2023

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