KIR+CD8+ T cells

1. KIR+CD8+ T cells increase cell killing (cytotoxicity) in humans.

   “IL-15-induced NK-like cytotoxicity is prominent in KIR+CD8+ T cells.”

   Humansin response to IL-15

   KIR⁺CD8⁺ and NKG2A⁺CD8⁺ T cells are distinct innate-like populations in humans

   Cell reports·Mar 9, 2023

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1. KIR+CD8+ T cells increase cellular senescence in humans.

   “KIR+CD8+ T cells are more terminally differentiated and replicative senescent than NKG2A+CD8+ T cells.”

   Humanscompared with NKG2A+CD8+ T cells

   KIR⁺CD8⁺ and NKG2A⁺CD8⁺ T cells are distinct innate-like populations in humans

   Cell reports·Mar 9, 2023

More on Cellular senescence