isoDGR-protein levels

1 paper1 finding

Animals1

Interventions

1

Anti-isodgr mab

downin mice1

1 study

Anti-isodgr mab decreases isoDGR-protein levels in mice.
“weekly injection of anti-isoDGR mAb (1 mg/kg) was sufficient to significantly reduce isoDGR-protein levels in body tissues”
AnimalsPcmt1-/- mouse1 mg/kg
Immunotherapy targeting isoDGR-protein damage extends lifespan in a mouse model of protein deamidation
EMBO molecular medicine16 Nov 2023

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EMBO Molecular Medicine16 Nov

Immunotherapy targeting isoDGR-protein damage extends lifespan in a mouse model of protein deamidation

Experiments in miceInterventions