What does the research say about iPACE?

iPACE

There is 1 paper on iPACE in aging research: 1 observational study in people. The newest story, Nov 3, 2026: “Immune protein pattern linked to heart disease risk in older adults”.

Biomarker

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1 new paper in 30 daysSee all 12

“a thirty-protein signature of age based on serum immune proteomics, which correlates with HFpEF and ASCVD risk and mortality”

Immuno-Proteomic Age of Cardiovascular Etiology (iPACE) Signature Predicts Cardiovascular Risk in Elderly PatientsbioRxiv2026doi:10.64898/2026.10.27.762320

Humans1

Associations

Mortality

mixedin humans1

1 study

iPACE is associated with mortality in humans.
“a thirty-protein signature of age based on serum immune proteomics, which correlates with HFpEF and ASCVD risk and mortality”
Humans
Immune protein pattern linked to heart disease risk in older adults
bioRxivNov 2, 2026Preprint

Atherosclerotic cardiovascular disease risk

mixedin humans1

1 study

iPACE is associated with atherosclerotic cardiovascular disease risk in humans.
“a thirty-protein signature of age based on serum immune proteomics, which correlates with HFpEF and ASCVD risk and mortality”
Humans
Immune protein pattern linked to heart disease risk in older adults
bioRxivNov 2, 2026Preprint

Heart failure with preserved ejection fraction risk

mixedin humans1

1 study

iPACE is associated with heart failure with preserved ejection fraction risk in humans.
“a thirty-protein signature of age based on serum immune proteomics, which correlates with HFpEF and ASCVD risk and mortality”
Humans
Immune protein pattern linked to heart disease risk in older adults
bioRxivNov 2, 2026Preprint

Latest

4 papers in 12 months

bioRxivNov 3

Immune protein pattern linked to heart disease risk in older adults

An observational preprint used two independent groups of older adults to develop a 30-protein age signature associated with cardiovascular risk and mortality.An observational preprint used two independent groups of older adults to develop a 30-protein age signature associated with cardiovascular risk and mortality.

Preprint: cohort studyBiomarkers