Insulin-like peptide 3

2 papers3 findings

Humans1

Associations

3

Premature ovarian insufficiency

upin humans1

1 study

Insulin-like peptide 3 predicts premature ovarian insufficiency in humans (AUC: 0.711).
“INSL3 showed moderate effectiveness in detecting both DOR (area under the curve [AUC]: 0.685) and POI (AUC: 0.711)”
Humansovarian reserve assessmentfemalesn = 179
Evaluating the efficacy of potential ovarian reserve markers from theca and granulosa cells: INSL3 & TNFR2
Medicine27 Jun 2025

More on Premature ovarian insufficiency

Decreased ovarian reserve

upin humans1

1 study

Insulin-like peptide 3 predicts decreased ovarian reserve in humans (AUC: 0.685).
“INSL3 showed moderate effectiveness in detecting both DOR (area under the curve [AUC]: 0.685) and POI (AUC: 0.711)”
Humansovarian reserve assessmentfemalesn = 179
Evaluating the efficacy of potential ovarian reserve markers from theca and granulosa cells: INSL3 & TNFR2
Medicine27 Jun 2025

More on Decreased ovarian reserve

PCOS

upin humans1

1 study

Insulin-like peptide 3 is associated with PCOS in humans.
“it is consequently increased in PCOS and decreased in women with premature ovarian failure (POF).”
ReviewPCOS
Insulin-like peptide 3 (INSL3) is a major regulator of female reproductive physiology
Human reproduction update1 Nov 2018

Latest

1 in 12 months

Frontiers in Endocrinology9 Jul

Klinefelter syndrome beyond hypogonadism: multisystem manifestations and a framework for clinical surveillance

ReviewHypogonadism

Medicine1 Jul

Evaluating the efficacy of potential ovarian reserve markers from theca and granulosa cells: INSL3 & TNFR2

Cohort study of 179 peopleBiomarkers

Andrology1 Jul

Association of age, hormonal, and lifestyle factors with the Leydig cell biomarker INSL3 in aging men from the European Male Aging Study cohort

Study in peopleBiomarkers

Human Reproduction Update1 Nov

Insulin-like peptide 3 (INSL3) is a major regulator of female reproductive physiology

ReviewReproductive system