Innate immune gene expression

1 paper studies it4 more mention it1 finding

Model organisms1

Interventions

1

Naltrexone

upin worms1

1 study

Naltrexone increases innate immune gene expression in worms.
“LDN treatment not only increased the expression of innate immune genes but also activated the oxidative stress response in worms”
Model organismslow dose
Low-dose Naltrexone (LDN) extends healthspan and lifespan through activation of the transcription factor SKN-1/NRF2 in C. elegans
Research SquareJun 14, 2023Preprint

More on Naltrexone

Latest

Global Change BiologyAug 5

Fluctuating Warm and Humid Conditions Differentially Impact Immunity and Development in the Malaria Vector Anopheles stephensi

Experiments in model organismsMechanisms

iScienceMay 27

Low-dose naltrexone extends healthspan and lifespan in C. elegans via SKN-1 activation

Experiments in wormsInterventions

Research SquareJun 14

Low-dose Naltrexone (LDN) extends healthspan and lifespan through activation of the transcription factor SKN-1/NRF2 in C. elegans

Preprint: experiments in wormsInterventions

eLifeMay 23

Tau polarizes an aging transcriptional signature to excitatory neurons and glia

Experiments in fliesMechanisms

BiologyFeb 26

Selective Destabilization of Transcripts by mRNA Decapping Regulates Oocyte Maturation and Innate Immunity Gene Expression during Ageing in C. elegans

Experiments in wormsMechanisms