Immunosenescent CD4+ T cells
Biomarker1 paper2 findings
- Animals1
Associations
1Chronic inflammatory demyelinating polyneuropathy
upin humans1upin mice1
1 study
Chronic inflammatory demyelinating polyneuropathy
upin humans1upin mice1
Chronic inflammatory demyelinating polyneuropathy is associated with immunosenescent CD4+ T cells in mice.
Animalsin mice with CIDP-like disease
Senescent CD4 T cells drive age-associated autoimmunity in mice and humans · bioRxiv : the preprint server for biology · 22 Sep 2026 · Preprint
Chronic inflammatory demyelinating polyneuropathy is associated with immunosenescent CD4+ T cells in humans.
Humansin CIDP patients
Senescent CD4 T cells drive age-associated autoimmunity in mice and humans · bioRxiv : the preprint server for biology · 22 Sep 2026 · Preprint
Latest
1Senescent CD4 T cells drive age-associated autoimmunity in mice and humans
Targeting senescent immune cells with fisetin or ruxolitinib reduced disease features and protected mice against autoimmune peripheral nerve damage.Targeting senescent immune cells with fisetin or ruxolitinib reduced disease features and protected mice against autoimmune peripheral nerve damage.