There are 4 papers on IL-1β maturation in aging research: none in people yet, 4 in animals.
4 papers study it2 more mention it1 finding
See all 6 papers on IL-1β maturation
- Animals4
Upstream
1PSMD14
downin mouse cells1
1 study
PSMD14
downin mouse cells1
PSMD14 inhibits IL-1β maturation in mouse cells (shown by ISG15-mediated degradation of PSMD14).
“the degradation of ISGylated PSMD14 suppressed the K63-linked ubiquitination of Pro-IL-1β, and eventually facilitated inflammatory cytokine IL-1β maturation”
Cellsshown by ISG15-mediated degradation of PSMD14
Inhibition of the ISG15 prevents inflammation-dependent ovarian aging
The journals of gerontology. Series A, Biological sciences and medical sciences
Latest
1 paper in 12 monthsJournal of Physiology and Biochemistry
Protective effect of melatonin against age-related ischemia-reperfusion injury is associated with the NLRP3 inflammasome pathway
Experiments in ratsMelatonin
The Journals of Gerontology, Series A
Inhibition of the ISG15 prevents inflammation-dependent ovarian aging
Experiments in miceInflammation
Neurobiology of Disease
Thioredoxin interacting protein regulates age-associated neuroinflammation
Experiments in miceInflammation
Nature Communications
Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting
Experiments in miceNLRP3 inflammasome
Neurochemistry International
Activation of NLRP3-Caspase-1 pathway contributes to age-related impairments in cognitive function and synaptic plasticity
Experiments in ratsNLRP3
Methods in Molecular Biology
Measuring the Inflammasome in Oncogene-Induced Senescence
Study protocolCellular senescence