IGF1R phosphorylation
1 paper1 finding
- Animals1
Upstream
1EI24
downin mice1
1 study
EI24
downin mice1
EI24 decreases IGF1R phosphorylation in mice.
“EI24 was found to bind to IGF1R, specifically engaging with its transmembrane (TM) domain near the cytoplasmic membrane, and suppress its phosphorylation.”
Animals
EI24 binds to IGF1R, enhancing glucose homeostasis and fostering healthy aging in male mice
Frontiers in aging10 Jun 2025
Latest
1 in 12 monthsEuropean Journal of Pharmacology
Isoliensinine ameliorates postoperative neurocognitive disorder in aged mice by restoring hippocampal IGF-1 receptor signaling and suppressing oxidative stress and neuroinflammation
Experiments in miceInterventions
Frontiers in Aging
EI24 binds to IGF1R, enhancing glucose homeostasis and fostering healthy aging in male mice
Experiments in miceMechanisms