AgingResearch.NewsJoin free

IFNγ to IL-10 ratio

There is 1 paper on IFNγ to IL-10 ratio in aging research: 1 trial in people.

Biomarker

1 paper studies it2 findings

See all 1

  • Human trial1

Interventions

1

High-dose split-virus influenza vaccine

downin humans1

1 study

  1. High-dose split-virus influenza vaccine decreases IFNγ to IL-10 ratio in humans (std. β -0.22, 95% CI -0.24 to -0.19).

    “The IFNγ:IL-10 ratio was significantly increased in males vs. females [std. β (95% CI) = 0.25 (0.11, 0.39)] and significantly lower in HD vs. SD recipients [−0.22 (−0.24, −0.19)] and pre-frail [−0.25 (−0.30, −0.21)] and frail [−0.10 (−0.19, −0.02)] vs. robust older adults.”

    Human trial20 weeksn = 582

    Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults

    Frontiers in aging

  2. High-dose split-virus influenza vaccine decreases IFNγ to IL-10 ratio in humans.

    “Relative to SD-SVV recipients, older HD-SVV recipients exhibited significantly lower IFNγ:IL-10 ratios at 4 weeks post-vaccination.”

    Human trial4 weeksn = 582

    Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults

    Frontiers in aging

More on High-dose split-virus influenza vaccine

Latest

Related