Hprt mutant frequency
2 papers2 findings
- Animals1
Interventions
1Caloric restriction
downin rats1downin reviews1
2 studies
Caloric restriction
downin rats1downin reviews1
Caloric restriction decreases Hprt mutant frequency in rats.
“The mutant frequency in the BLM-treated rats was higher in AL males (P=0.001), and AL females (P=0.0174) than in their calorie-restricted counterparts.”
Animalsbleomycin-treated40% calorie restrictionspleen4 weeks post drug treatmentmales
Mutation researchNov 29, 1999
Caloric restriction decreases Hprt mutant frequency.
“Dietary restriction, which prolongs life span, results in slowed accumulation of HPRT mutants in mice.”
Reviewin mice
Annals of the New York Academy of SciencesNov 20, 1998
Latest
Mutation Research
Attenuation of bleomycin-induced Hprt mutant frequency in female and male rats by calorie restriction
Experiments in ratsDietary restriction