Hippocampal volume decline

Biomarker

2 papers2 findings

  • Humans2

Interventions

1

Low social network heterogeneity

upin humans1

1 study
  1. Low social network heterogeneity increases hippocampal volume decline in humans.

    “lower heterogeneity in social networks was linked to greater hippocampal volume decline, after adjusting for sociodemographic factors and health behaviors.”

    Humanshippocampusn = 279

    Diversity in social networks and brain aging in community-dwelling older adults in Japan: The NEIGE Study

    GSA 2025 abstract31 Dec 2025

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Associations

1

Perceived constraints

upin humans1

1 study
  1. Perceived constraints are associated with hippocampal volume decline in humans.

    “Greater constraints related to greater baseline hippocampal volume for Black participants, but faster hippocampal volume decline for White participants.”

    HumansWhite participants

    Perceived control, brain health, and cognitive reserve: longitudinal resilience mechanisms in Black, White, and Hispanic older adults

    The journals of gerontology. Series B, Psychological sciences and social sciences19 Dec 2025

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