Hippocampal cytokines

1. TNF-alpha increases hippocampal cytokines in mice (subcutaneous recombinant administration in TLR4-/- mice exposed to sevoflurane).

   “Subcutaneous administration of recombinant TNF-α elevated these cytokine levels in the hippocampus”

   Animalssubcutaneous recombinant administration in TLR4-/- mice exposed to sevofluranerecombinanthippocampus

   Sevoflurane-induced cognitive decline in aged mice: Involvement of toll-like receptors 4

   Brain research bulletin·Sep 7, 2020

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1. Acetaminophen is associated with hippocampal cytokines in rats (tibial fracture surgery model of POCD).

   “paracetamol showed modulatory effects on hippocampal cytokines and markers of microtubule dynamics which were suggestive of neuroprotection”

   Animalstibial fracture surgery model of POCDhippocampus

   Paracetamol (acetaminophen) as potential first-choice analgesic in post-operative cognitive decline (POCD): Behavioral and molecular evidence in a middle-aged rat model

   Research Square·Dec 18, 2020Preprint

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