High-frequency heart rate variability

Biomarker

3 papers4 findings

  • Human trial1
  • Humans1
  • Animals1

Interventions

1

Dietary restriction

upin rats1

1 study
  1. Dietary restriction increases high-frequency heart rate variability in rats.

    “the high-frequency component of HRV spectra, a marker for parasympathetic activity, was increased.”

    Animalsat least 1 monthmales

    Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology1 Apr 2006

More on Dietary restriction

Associations

3

Cognitive flexibility

upin humans1

1 study
  1. High-frequency heart rate variability is associated with cognitive flexibility in humans (β = 0.02, 95% CI = 0.00, 0.04, p = .03).

    “and the Dimensional Change Card Sort Test ( β = 0.02, 95% CI = 0.00, 0.04, p = .03), but was not associated with the other tests.”

    Humansheart failure and mild cognitive impairmentn = 54

    Vagal Control and Cognitive Function among Patients with Heart Failure and Mild Cognitive Impairment

    AHA Scientific Sessions 2025 abstract3 Nov 2025

Episodic memory

upin humans1

1 study
  1. High-frequency heart rate variability is associated with episodic memory in humans (β = 0.02, 95% CI = 0.01, 0.03, p = .001).

    “higher scores on the Picture Sequence Memory Test ( β = 0.02, 95% CI = 0.01, 0.03, p = .001)”

    Humansheart failure and mild cognitive impairmentn = 54

    Vagal Control and Cognitive Function among Patients with Heart Failure and Mild Cognitive Impairment

    AHA Scientific Sessions 2025 abstract3 Nov 2025

Fluid cognition

upin humans1

1 study
  1. High-frequency heart rate variability is associated with fluid cognition in humans (β = 0.02, 95% CI = 0.01, 0.03, p = .01).

    “Higher HF-HRV was associated with higher Fluid Cognition Composite score ( β = 0.02, 95% CI = 0.01, 0.03, p = .01)”

    Humansheart failure and mild cognitive impairmentn = 54

    Vagal Control and Cognitive Function among Patients with Heart Failure and Mild Cognitive Impairment

    AHA Scientific Sessions 2025 abstract3 Nov 2025

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