HDAC activity

1 paper studies it10 more mention it

Human trial1

Latest

2 papers in 12 months

Cancer Prevention ResearchOct 28

Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy

Randomized trial in 54 peopleInterventions

BloodAug 24

Ferroptotic stress promotes hematopoietic stem cell aging through S1P-dependent epigenetic and lipid remodeling

Experiments in miceFerroptosis

Journal of Cachexia, Sarcopenia and MuscleJul 20

Cigarette Smoke-Exposed Alveolar Epithelial Cell-Derived Exosomes Exacerbate Skeletal Muscle Dysfunction Through HDAC2 Signalling

Experiments in miceMuscle

Drug Discovery TodayJul 10

Targeting histone deacetylases: Emerging applications beyond cancer

ReviewInterventions

Medical HypothesesNov 10

Histone deacetylase inhibition improves metabolism and mitochondrial dynamics: A potential novel therapeutic strategy for sarcopenia coexisting with diabetes mellitus

CommentaryMitochondrial fission and fusion

EMedical ResearchJan 1

Therapeutic Targeting of Histone Deacetylation to Prevent Alzheimer's Disease

ReviewInterventions

American Journal of Physiology Regulatory, Integrative and Comparative PhysiologyJun 13

Skeletal muscle LINE-1 retrotransposon activity is upregulated in older versus younger rats

Experiments in animalsMechanisms

Neuroscience LettersMay 21

Exercise enhances the expression of brain-derived neurotrophic factor in the hippocampus accompanied by epigenetic alterations in senescence-accelerated mice prone 8

Experiments in animalsInterventions

Experimental GerontologyOct 12

Sodium butyrate improves memory and modulates the activity of histone deacetylases in aged rats after the administration of d-galactose

Experiments in animalsInterventions

International Journal of Clinical and Experimental PathologyJan 1

Involvement of spinal SIRT1 in development of chronic constriction injury induced neuropathic pain in rats

Experiments in ratsSirtuin signaling