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MechanismsAnimals

Ferroptotic stress promotes hematopoietic stem cell aging through S1P-dependent epigenetic and lipid remodeling

Blood

  • SPHK2
  • Ferroptosis
  • Histone modification and chromatin remodelling
  • Aged HSCs
  • LPCAT2
  • Mice

The paper

Zhao Y, Li Y, Tian X et al.

Blood · 24 Aug 2026

doi.org/10.1182/blood.2026034204PubMed 42636157

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