Gut microbiome signature

1. Gut microbiome signature predicts physical function in humans.

   “Using Receiver Operating Characteristic (ROC) curve analysis, we demonstrated that specific microbial signatures accurately distinguish between individuals with low and high physical function.”

   Humansolder adults

   Early Detection of Physical Function Decline in Older Adults by Identifying Gut-Microbiome Based Biomarkers

   GSA 2025 abstract·31 Dec 2025

1. Gut microbiome signature predicts cognitive impairment in humans.

   “Our results suggest that microbiome signatures predict cancer survivorship and the risk of CI in older adults, potentially by depleting neurotransmitter synthesis in the gut.”

   Humanscancer survivorsgutn = 150

   Gut microbiome signatures predict cognitive impairment in older cancer survivors

   GeroScience·1 Nov 2025

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