Glucose output
2 papers2 findings
- Animals1
- Cells1
Interventions
2Tetradecanoylphorbol acetate
downin rat cells1
1 study
Tetradecanoylphorbol acetate
downin rat cells1
Tetradecanoylphorbol acetate decreases glucose output in rat cells.
“Both pathways were inhibited by the protein kinase C (PKC) activator, 4 beta-phorbol 12-myristate 13-acetate (PMA); the inhibitory effect was decreased in hepatocytes from mature adult and senescent rats.”
Cellsin hepatocytes from mature adult and senescent ratsliver
Influence of aging on the alpha 1-receptor-mediated glycogenolysis in rat hepatocytes
Journal of gerontology1 Jan 1994
Propranolol
downin rat cells1
1 study
Propranolol
downin rat cells1
Propranolol inhibits glucose output in rat cells.
“The isoproterenol-stimulated glucose output in hepatocytes from senescent rats was inhibited concentration dependently by propranolol, ICI 118,551, ICi 89,406, and CGP 20,712A.”
Cellsconcentration dependentlyhepatocytes
Influence of age on the beta 1- and beta 2-adrenergic receptors in rat liver
Molecular pharmacology1 Oct 1992
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2 in 12 monthsmedRxiv
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Experiments in miceSirtuin signalling
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Preprint: experiments in miceSirtuin signalling
Drug Design, Development and Therapy
Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes
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Nature Communications
Restoration of energy homeostasis by SIRT6 extends healthy lifespan
Experiments in miceInterventions
JCI Insight
SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside
Experiments in animalsInterventions
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Altered expression of hepatic β-adrenergic receptors in aging rats: implications for age-related metabolic dysfunction in liver
Experiments in ratsMechanisms
Journal of Gerontology
Influence of aging on the alpha 1-receptor-mediated glycogenolysis in rat hepatocytes
Experiments in rat cellsMechanisms
Molecular Pharmacology
Influence of age on the beta 1- and beta 2-adrenergic receptors in rat liver
Experiments in ratsMechanisms