GluA1 currents

1. GPER1 mediates GluA1 currents in mice.

   “Heightened GluA1 currents in hypertensive post-AOF mice appeared to be mediated by an uncoventional AMPA receptor-AKAP150-associated G-protein coupled estrogen receptor 1 (GPER1) signaling pathway.”

   Animalsin hypertensive post-AOF miceparaventricular hypothalamic nucleusfemales

   G-protein coupled estrogen receptor 1 contributes to suppression of angiotensin II hypertension via modulation of AMPA GluA1 in the hypothalamic paraventricular nucleus in a mouse model of post-menopause

   Biology of sex differences·23 May 2026

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