Genomic spread of γH2AX

Biomarker

1 paper1 finding

  • Cells1

Upstream

1

HDAC4

downin cells1

1 study
  1. HDAC4 decreases genomic spread of γH2AX in cells.

    “Forced expression of HDAC4 during RAS-induced senescence reduces the genomic spread of γH2AX.”

    CellsForced HDAC4 expression during RAS-induced senescence

    HDAC4 influences the DNA damage response and counteracts senescence by assembling with HDAC1/HDAC2 to control H2BK120 acetylation and homology-directed repair

    Nucleic acids research14 Jun 2024

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