Frontal QRS-T angle

1. Frontal QRS-T angle is associated with hypertrophic cardiomyopathy in humans (Multivariate logistic regression) (Adjusted OR per 1° increase 1.023; 95% CI 1.008-1.039; p = 0.003).

   “frontal QRS-T angle was independently associated with HCM (adjusted OR per 1° increase 1.023; 95% CI 1.008-1.039; p = 0.003).”

   HumansMultivariate logistic regressionper 1° increase

   Screening for hypertrophic cardiomyopathy in adults using ECG-derived frontal QRS-T angle

   Journal of electrocardiology·Oct 9, 2026

2. Frontal QRS-T angle predicts hypertrophic cardiomyopathy in humans (AUC 0.711 (95% CI 0.520-0.901); sensitivity 67% and specificity 86% at 44.5°).

   “the frontal QRS-T angle demonstrated fair discriminatory ability for HCM detection, with an area under the ROC curve (AUC) of 0.711 (95% CI 0.520-0.901).”

   HumansPrimary definition: septal or posterior left ventricular wall thickness ≥15 mm in the absence of hypertensionn = 3,133

   Screening for hypertrophic cardiomyopathy in adults using ECG-derived frontal QRS-T angle

   Journal of electrocardiology·Oct 9, 2026

More on Hypertrophic cardiomyopathy

1. Frontal QRS-T angle is associated with heart failure in humans (cardiology outpatients) (46.7% vs. 29.2%, p=0.004).

   “heart failure (46.7% vs. 29.2%, p=0.004)”

   Humanscardiology outpatients12-monthn = 290

   FRONTAL QRS-T ANGLE AND MULTISYSTEM STRESS: A NONINVASIVE MARKER ?

   Kocatepe Tıp Dergisi·Jul 20, 2026

More on Heart failure

1. Frontal QRS-T angle is associated with coronary artery disease in humans (cardiology outpatients) (89.1% vs. 79.5%, p=0.045).

   “coronary artery disease (89.1% vs. 79.5%, p=0.045)”

   Humanscardiology outpatients12-monthn = 290

   FRONTAL QRS-T ANGLE AND MULTISYSTEM STRESS: A NONINVASIVE MARKER ?

   Kocatepe Tıp Dergisi·Jul 20, 2026

More on Coronary artery disease

1. Frontal QRS-T angle is associated with diabetes mellitus in humans (cardiology outpatients) (53.3% vs. 37.6%, p=0.013).

   “Patients with a QRS-T angle ≥90° had significantly higher rates of diabetes (53.3% vs. 37.6%, p=0.013)”

   Humanscardiology outpatients12-monthn = 290

   FRONTAL QRS-T ANGLE AND MULTISYSTEM STRESS: A NONINVASIVE MARKER ?

   Kocatepe Tıp Dergisi·Jul 20, 2026

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1. Schizophrenia is associated with frontal QRS-T angle in humans (compared with healthy controls) (MD = 26.11°, 95% CI 19.10-33.11).

   “demonstrated pronounced abnormalities, including an increased frontal QRS-T angle (MD = 26.11°, 95% CI 19.10-33.11)”

   Reviewcompared with healthy controls

   Ventricular repolarization heterogeneity in schizophrenia: A systematic review and meta-analysis of traditional and novel ECG markers

   Asian journal of psychiatry·Mar 21, 2026

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