FOXO3a acetylation

1 paper studies it1 more mentions it1 finding

Animals1

Upstream

1

SIRT1

downin mice1

1 study

SIRT1 decreases FOXO3a acetylation in mice.
“Sirt1 overexpression in MSCs reduced the acetylation level of FOXO3a (Forkhead box O3a)”
Animalsbony tissue
Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition
Metabolism: clinical and experimentalJul 3, 2018

Latest

Aging CellJun 9

TRIM33 protects osteoblasts from oxidative stress-induced apoptosis in osteoporosis by inhibiting FOXO3a ubiquitylation and degradation

Study in peopleMechanisms

MetabolismJul 3

Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition

Experiments in miceBones and joints