Fibrillarin

1 paper

Model organisms1

Latest

3 in 12 months

Advanced Science10 Aug

Fibrillarin Resists Cellular Senescence Via SIRT1-Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma

Experiments in human cellsNAD+ metabolism

Nature Communications7 Apr

ASO therapy rescues NOTCH2NLC GGC repeat expansion-induced genomic damage, 3D chromatin structural abnormalities, and senescence

Experiments in cellsInterventions

Biomedicines27 Nov

Loss of AT8 Nuclear Tau as a Marker of Neuronal Ageing and Alzheimer's Disease Progression

Cross-sectional study in peopleMechanisms

PLOS One3 Nov

Aging influences nucleolar responses to traumatic brain injury in Drosophila

Experiments in fliesMechanisms

Neurochemistry International28 Mar

The C. elegans glutamate transporters GLT-4 and GLT-5 regulate protein expression, behavior, and lifespan

Experiments in model organismsMechanisms

Redox Biology8 Aug

Reduced dynamicity and increased high-order protein assemblies in dense fibrillar component of the nucleolus under cellular senescence

Experiments in cellsMechanisms

Nature Communications30 Aug

Small nucleoli are a cellular hallmark of longevity

Experiments in wormsMechanisms