Extracellular free water

Biomarker

1 paper2 findings

Humans1

Effects

Fractional anisotropy

mediatesin humans1

1 study

Extracellular free water mediates fractional anisotropy in humans.
“Mediation analyses revealed that fornix FW mediated the relationship between DTI-ALPS and both fornix FA and hippocampal FW.”
Humansin autistic adultsfornix
Association of glymphatic dysfunction, free water, white matter integrity and long-term memory performance in aging autistic adults
Molecular autism18 Feb 2026

Upstream

Autism

upin humans1

1 study

Autism increases extracellular free water in humans.
“Autistic adults showed significantly lower DTI-ALPS values, higher fornix FW, lower fornix FA, and poorer episodic memory scores compared to NT adults.”
Humansin autistic adults compared to neurotypical adultsfornix
Association of glymphatic dysfunction, free water, white matter integrity and long-term memory performance in aging autistic adults
Molecular autism18 Feb 2026

Latest

5 in 12 months

Imaging Neuroscience11 Oct

Brain scans suggest poorer fluid clearance in older adults

A cross-sectional study of 30 healthy adults linked older age to brain scan measures suggesting impaired fluid clearance and altered barrier function.A cross-sectional study of 30 healthy adults linked older age to brain scan measures suggesting impaired fluid clearance and altered barrier function.

Cross-sectional study of 30 peopleMechanisms

Paper

Neurobiology of Aging1 Sep