Expression of PPAR-γ lipogenic target genes

1. NAMPT increases expression of PPAR-γ lipogenic target genes in mice.

   “loss of Nampt caused marked decreases in WAT gene expression of lipogenic targets of peroxisome proliferator-activated receptor gamma (PPAR-γ) in an age-dependent manner.”

   Animalsshown by adipocyte-specific Nampt loss; age-dependent effectwhite adipose tissuefemales

   Adipocyte-specific inactivation of NAMPT, a key NAD⁺ biosynthetic enzyme, causes a metabolically unhealthy lean phenotype in female mice during aging

   American journal of physiology. Endocrinology and metabolism·May 29, 2024

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