There are 6 papers on Escherichia-Shigella in aging research: 5 observational studies in people, 1 in animals.
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“EATVI was significantly negatively correlated with post-conversion abundance of Escherichia coli (R = -0.496, P = 0.019) and Escherichia Shigella (R = -0.472, P = 0.027) in HFrEF_AF patients.”
- Humans5
- Animals1
Interventions
1Hormone replacement therapy
downin humans1
1 study
Hormone replacement therapy
downin humans1
Hormone replacement therapy is linked with lower Escherichia-Shigella in humans.
“Escherichia-Shigella taxa was more abundant in MHT- group”
Humansstoolfemalesn = 31
Frontiers in medicine
Upstream
1Sarcopenia
upin humans1
1 study
Sarcopenia
upin humans1
Sarcopenia is linked with higher Escherichia-Shigella in aged patients with sarcopenia.
“pathogenic bacteria, such as Escherichia-Shigella and Klebsiella, were increased.”
Humansin aged patients with sarcopeniastool
Experimental gerontology
Associations
4Left atrial anteroposterior diameter
downin humans1
1 study
Left atrial anteroposterior diameter
downin humans1
Escherichia-Shigella is associated with left atrial anteroposterior diameter in humans (indirect effect through EATVI in mediation analysis, HFrEF_AF patients) (ACME = -0.553).
“The mediation analysis showed that Escherichia Shigella in HFrEF_AF patients had a significant indirect effect on LAAD through EATVI (ACME = -0.553, P = 0.042)”
Human trialindirect effect through EATVI in mediation analysis, HFrEF_AF patientsn = 26
Frontiers in cardiovascular medicine
Epicardial adipose tissue volume index
downin humans1
1 study
Epicardial adipose tissue volume index
downin humans1
Escherichia-Shigella is associated with epicardial adipose tissue volume index in HFrEF_AF patients, adjusted for age, gender, CHD and BMI (R = -0.472).
“EATVI was significantly negatively correlated with post-conversion abundance of Escherichia coli (R = -0.496, P = 0.019) and Escherichia Shigella (R = -0.472, P = 0.027) in HFrEF_AF patients.”
Human trialin HFrEF_AF patients, adjusted for age, gender, CHD and BMIepicardial adipose tissuen = 26
Frontiers in cardiovascular medicine
Frailty
upin humans1
1 study
Frailty
upin humans1
Escherichia-Shigella predicts frailty in humans (frail older adults).
“Specifically, Escherichia-Shigella was significantly upregulated and fit well into the prediction model of frailty.”
Humansfrail older adults
Analysis of alterations in the composition of the intestinal microbiota in frail older individuals
PloS one
Muscle mass
downin humans1
1 study
Muscle mass
downin humans1
Escherichia-Shigella is associated with muscle mass in aged patients with sarcopenia.
“the abundances of Escherichia-Shigella and Enterobacteriaceae have been found to have a negative correlation with muscle mass”
Humansin aged patients with sarcopeniastool
Experimental gerontology