Epigenetic aging acceleration

Biomarker

1 paper3 findings

  • Humans1

Associations

3

Social determinants of health

upin humans1

1 study
  1. social determinants of health is associated with epigenetic aging acceleration in humans.

    “SDOH was associated with greater aging accel”

    Humansfemalesn = 1,500

    Accelerated Epigenetic Aging in Diabetes: Socio-Biological Pathways of Health Inequity

    Aging and disease3 Aug 2026

Insulin resistance

upin humans1

1 study
  1. Epigenetic aging acceleration is associated with insulin resistance in humans.

    “Greater aging accel was observed in T2DM, albeit with only univariate significance and IR”

    Humanscross-section at baselinefemalesn = 1,500

    Accelerated Epigenetic Aging in Diabetes: Socio-Biological Pathways of Health Inequity

    Aging and disease3 Aug 2026

More on Insulin resistance

Type 2 diabetes

upin humans1

1 study
  1. Epigenetic aging acceleration is associated with type 2 diabetes in humans.

    “Greater aging accel was observed in T2DM, albeit with only univariate significance”

    Humansunivariate significancefemalesn = 1,500

    Accelerated Epigenetic Aging in Diabetes: Socio-Biological Pathways of Health Inequity

    Aging and disease3 Aug 2026

More on Type 2 diabetes

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medRxiv

Hormone therapy linked to lower breast cancer mortality

Compared with never-users, hormone therapy ever-users had adjusted hazard ratios, which compare event rates over time, of 0.72 for breast cancer death and 1.17 for…Compared with never-users, hormone therapy ever-users had adjusted hazard ratios, which compare event rates over time, of 0.72 for breast cancer death and 1.17 for diagnosis.

Preprint: cohort study of 78,209 peopleBreast cancer
medRxiv

Accelerated epigenetic aging predicts major depression and brain changes after trauma

Emergency department measurements of GrimAge and DunedinPACE biological aging markers tracked subsequent depressive symptoms and neural connectivity shifts in adults over…Emergency department measurements of GrimAge and DunedinPACE biological aging markers tracked subsequent depressive symptoms and neural connectivity shifts in adults over 35.

Preprint: cohort study of 706 peopleGrimAge