DTI-ALPS mapping
2 papers5 findings
- Humans2
Associations
4Cognitive function
upin humans2
2 studies
Cognitive function
upin humans2
DTI-ALPS mapping is associated with cognitive function in humans (26 of 30 regions; 11 of 30 regions).
“Twenty‐six of 30 regions in the DTI‐ALPS mapping showed a positive correlation with MoCA, and 11 of these regions were also positively correlated with MMSE”
Humansacross cognitively unimpaired, MCI, and dementia participantscerebral white matter
DTI‐ALPS Mapping: A Novel Voxel‐based Method for Analyzing the Glymphatic System in the Brain
AAIC 2025 abstract26 Dec 2025
DTI-ALPS mapping is associated with cognitive function in humans (26/30 regions with MoCA, 11/30 with MMSE (p < 0.05)).
“Twenty‐six of 30 regions in the DTI‐ALPS mapping showed a positive correlation with MoCA, and 11 of these regions were also positively correlated with MMSE (Spearman, p < 0.05)”
Humanscerebral white mattern = 304
DTI‐ALPS Mapping: A Novel Voxel‐based Method for Analyzing the Glymphatic System in the Brain
AAIC 2025 abstract23 Dec 2025
White matter hypointensities
downin humans1
1 study
White matter hypointensities
downin humans1
DTI-ALPS mapping is associated with white matter hypointensities in humans (26 of 30 regions).
“Moreover, 26 of 30 regions showed a negative correlation with WMH (Spearman, p < 0.05).”
Humansacross cognitively unimpaired, MCI, and dementia participantscerebral white matter
DTI‐ALPS Mapping: A Novel Voxel‐based Method for Analyzing the Glymphatic System in the Brain
AAIC 2025 abstract26 Dec 2025
White matter hypointensities
downin humans1
1 study
White matter hypointensities
downin humans1
DTI-ALPS mapping is associated with White matter hypointensities in humans (26/30 regions (Spearman, p < 0.05)).
“Moreover, 26 of 30 regions showed a negative correlation with WMH (Spearman, p < 0.05).”
Humanscerebral white mattern = 304
DTI‐ALPS Mapping: A Novel Voxel‐based Method for Analyzing the Glymphatic System in the Brain
AAIC 2025 abstract23 Dec 2025
Intergroup differences
upin humans1
1 study
Intergroup differences
upin humans1
DTI-ALPS mapping is associated with intergroup differences in humans (>13/30 regions p < 0.05).
“Over 13 out of 30 regions exhibited significant differences ( p < 0.05) in the intergroup analyses, providing additional insights beyond those identified with conventional ROI‐based ALPS.”
Humansintergroup analyses (CU vs MCI vs dementia)cerebral white mattern = 304
DTI‐ALPS Mapping: A Novel Voxel‐based Method for Analyzing the Glymphatic System in the Brain
AAIC 2025 abstract23 Dec 2025