DNMT3b

4 papers2 findings

Humans1
Animals3

Interventions

1

Exercise

downin rats1

1 study

Exercise decreases DNMT3b in rats.
“The single exercise session decreased both DNMT3b and DNMT1 levels in young adult rats”
Animalshippocampus
Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study
Experimental gerontology30 Nov 2012

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Upstream

1

Age-related cataract

upin mice1

1 study

Age-related cataract increases DNMT3b in mice.
“the protein expression level of DNMT3B was elevated, while the protein expression levels of GJA3 and p-GSK-3β (Ser9) were decreased in the ARC group and the aged mouse group (P < 0.05).”
Animalsin aged mice and age-related cataractlens
The role of DNMT3B, GSK-3β and GJA3 in lens epithelial cell apoptosis and age-related cataract
BMC ophthalmology18 Jun 2026

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Latest

4 in 12 months

BMC Ophthalmology19 Jun

The role of DNMT3B, GSK-3β and GJA3 in lens epithelial cell apoptosis and age-related cataract

Case-control study in peopleCataract

Theriogenology10 May

Transcriptome and metabolome analysis reveals that cuproptosis in bovine cumulus cells triggers the intercellular transmission of senescence and mitochondrial dysfunction to impair oocyte quality

Experiments in cellsCellular senescence

Viruses27 Feb

HIV Infection as an Independent Factor Accelerating Epigenetic Ageing in Men Treated with Integrase Inhibitors: A Case-Control Study

Case-control study of 50 peopleHIV infection

Medicine3 Feb

Multi-omics data reveal causal associations of cellular senescence-related genes in rheumatoid arthritis: A summary-data-based Mendelian randomization and co-localization analysis

Computational studyCellular senescence

ENDO 2025 Abstract23 Oct

MON-707 Lifestyle Intervention Therapy Modulates Global and Gene Specific DNA Methylation In Severely Obese Hypogonadal Men

Non-randomised trial in 116 peopleHypogonadism

Communications Biology31 Aug

Mendelian randomization reveals potential causal relationships between cellular senescence-related genes and multiple cancer risks

Mendelian randomisation in peopleCellular senescence

Cell Death Discovery23 Jun

DNA methylation as an epigenetic mechanism in the regulation of LEDGF expression and biological response in aging and oxidative stress

Study in peopleMechanisms

Cell21 Jun

TERT activation targets DNA methylation and multiple aging hallmarks

Experiments in miceInterventions

Journal of Toxicology and Environmental Health Part A29 Mar

Mechanisms underlying LncRNA SNHG1 regulation of Alzheimer's disease involve DNA methylation

Experiments in miceEpigenetic regulation of gene expression

Histochemistry and Cell Biology8 Jun

The loss of global DNA methylation due to decreased DNMT expression in the postnatal mouse ovaries may associate with infertility emerging during ovarian aging

Experiments in miceEpigenetic regulation of gene expression