DNAm-estimated exhausted CD8+ T cell count

DNAm-estimated exhausted CD8+ T cell count is associated with mortality in humans.

“DNAm-based estimates of exhausted CD8 + T cell counts were higher in deceased subjects when compared to survived.”

Humanstype 2 diabetes; deceased compared with surviving subjectsperipheral blood leukocytes16.8 yearsn = 50

DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes

Cardiovascular diabetology·13 Jul 2024