DNA double-strand break repair protein expression

Older age is associated with DNA double-strand break repair protein expression in mice.

“In aged groups, RAD51, BRCA1, KU80, and XRCC4 levels increased (P < 0.05), while RPA70 levels decreased (P < 0.05) compared to the other groups.”

Animalsaged groups compared with the other age groupsovaryfemales

The DNA double-strand break repair proteins γH2AX, RAD51, BRCA1, RPA70, KU80, and XRCC4 exhibit follicle-specific expression differences in the postnatal mouse ovaries from early to older ages

Journal of assisted reproduction and genetics·18 Jul 2024