Differentially expressed gene expression

Reproductive stage is associated with differentially expressed gene expression in worms.

“A similar analysis in C. elegans also showed a downregulation bias during the reproductive period, but the reproductive shift was absent.”

Model organismsduring the reproductive period; no post-reproductive reversal of the downregulation bias

Genome-wide temporal gene expression reveals a post-reproductive shift in the nematode C. briggsae

bioRxiv (Cold Spring Harbor Laboratory)·6 Jun 2024Preprint

Reproductive stage is associated with differentially expressed gene expression in C. briggsae (Majority of differentially expressed genes downregulated).

“analysis of differentially expressed (DE) genes revealed that the majority were downregulated during the reproductive period.”

Model organismsduring the reproductive period

Genome-wide temporal gene expression reveals a post-reproductive shift in the nematode C. briggsae

bioRxiv (Cold Spring Harbor Laboratory)·6 Jun 2024Preprint

Post-reproductive stage is associated with differentially expressed gene expression in C. briggsae (Three-quarters of genes upregulated).

“Interestingly, this trend reversed post-reproduction, with three-quarters of the genes upregulated—a phenomenon we termed the ‘reproductive shift’.”

Model organismsduring the post-reproductive period

Genome-wide temporal gene expression reveals a post-reproductive shift in the nematode C. briggsae

bioRxiv (Cold Spring Harbor Laboratory)·6 Jun 2024Preprint