Diethylthiophosphate

Diethylthiophosphate is associated with heart disease mortality in humans (HR 1.33, 95% CI 1.11-1.61).

“diethylthiophosphate (DETP) was associated with heart disease mortality after multivariable adjustment [hazard ratio 1.33, 95% confidence interval (CI) 1.11-1.61 per 1-SD increase, FDR = 0.010]”

Humansmultivariable adjustmentper 1-SD increasen = 502

Urinary organophosphate metabolites, DNA methylation aging, and heart disease mortality in middle-aged and older adults: an exploratory cohort study with in vitro evidence of biological plausibility

Frontiers in public health·31 Jul 2026