DELTA-6 desaturase activity

1. Dehydroepiandrosterone decreases DELTA-6 desaturase activity in humans.

   “Δ6-desaturase was significantly decreased in postmenopausal women after DHEA-S treatment”

   Human trialpostmenopausal obese womenoralplasma100mg/day3 monthsfemalesn = 41

   Dehydroepiandrosterone-sulphate replacement improves the human plasma fatty acid profile in plasma of obese women

   Steroids·Jul 27, 2011

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1. FADS1 is associated with DELTA-6 desaturase activity in humans.

   “rs174579 and rs174626 genotypes in FADS1/2 significantly affect delta-6 desaturase (D6D) activity”

   Humansblood

   Age-associated changes in circulatory fatty acids: new insights on adults and long-lived individuals

   GeroScience·Nov 30, 2022

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