DAF-16/FoxO

1 paper

Model organisms1

Latest

25 in 12 months

Biogerontology28 Sep

Perilla frutescens extract reduces fat accumulation and promotes longevity in Caenorhabditis elegans via modulation of the insulin/IGF-1 signaling pathway

Experiments in wormsInterventions

Biogerontology26 Sep

Turnera diffusa polysaccharides promote healthy aging through conserved stress response regulation and metabolic remodeling across multiple aging models

Experiments in wormsInterventions

Biogerontology19 Sep

Aging-modulatory effects of Pausinystalia macroceras (K. Schum.) Pierre polysaccharides are associated with DAF-16/FOXO and SKN-1/Nrf2 signaling in multiple aging models

Experiments in wormsInterventions

International Journal of Biological Macromolecules8 Sep

A homogalacturonan polysaccharide from Anemarrhena asphodeloides promotes longevity in Caenorhabditis elegans with involvement of DAF-16/FOXO

Experiments in wormsInterventions

bioRxiv21 Aug

TBC-2, a Rab GTPase activating protein, regulates the localization of the HLH-30/TFEB and PQM-1 transcription factors in the C. elegans intestine

Preprint: experiments in wormsGut and microbiome

Biogerontology13 Aug

Luteolin and glycitein from Codonopsis pilosula ameliorate age-related locomotor decline in C. elegans via DAF-16-dependent but autophagy-divergent pathways

Experiments in wormsInterventions

bioRxiv29 Jul

Supplementation via DAF-16 and pnk-1 driven pantothenate-coenzyme A flux improves disease related stress resistance in C. elegans

Preprint: experiments in wormsInterventions

Phytomedicine24 Jul

Quercetin alleviates MSG-induced oxidative toxicity and lifespan deterioration in Caenorhabditis elegans associated with SKN-1-gst-4 detoxification and DAF-16-dependent stress resilience

Experiments in wormsQuercetin

Ageing Research Reviews20 Jul

Phytochemicals modulating HSF-1-associated pathways: A systematic review of longevity-extending mechanisms in Caenorhabditis elegans

Systematic review of animal and cell studiesInterventions

Aging8 Jul

Inhibition of peroxisomal protein PRX-11 promotes longevity in Caenorhabditis elegans via enhancements to mitochondria

Experiments in wormsMitochondrion